KMID : 1225720160080060535
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Allergy, Asthma & Immunology Research : AAIR 2016 Volume.8 No. 6 p.535 ~ p.540
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A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children
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Lee So-Yeon
Kim Ji-Hyun Jang Gwang-Cheon Min Taek-Ki Kwon Ji-Won Sohn Myung-Hyun Kim Kyung-Won Kim Kyu-Earn Yu Jin-Ho Hong Soo-Jong Kwon Jung-Hyun Kim Sung-Won Song Tae-Won Kim Woo-Kyung Kim Hyung-Young Jeon You-Hoon Lee Yong-Ju Lee Hae-Ran Kim Hye-Young Ahn Young-Min Yum Hye-Yung Suh Dong-In Kim Hyun-Hee Kim Jin-Tack Kim Jeong-Hee Park Yong-Mean Lee Soo-Young Yang Hyeon-Jong Pyun Bok-Yang
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Abstract
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Purpose:Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children.
Methods:We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea.
Results:A total of 991 cases (mean age=5.89¡¾5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes.
Conclusions:The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
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KEYWORD
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Anaphylaxis, children, epidemiology
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